Roche and its subsidiary TIB Molbiol have developed a series of tests for the detection of the monkeypox virus, the Switzerland-based pharmaceutical company announced.
The monkeypox virus is a close relative of the smallpox virus, belonging to orthpoxviridae in the poxviridae family.
The modular virus detection tool, called LightMix, includes three orthpoxvirus detection kits with different functions, Roche said in a statement. The first kit detects orthpoxvirus; The second kit tests only for monkeypox virus (west and Central African branches); The third kit contains the main functions of the first two kits, showing specific information on the presence of the monkeypox virus (west and Central African branches) as well as the detection of orpoxvirus.
Thomas Schinek, a Roche executive, said the new test could detect monkeypox and help track its spread. Such diagnostic tools are critical for addressing and ultimately managing emerging public health challenges, as they advance responses such as tracking efforts and treatment strategies.
The monkeypox virus was first identified in 1958 in a group of monkeys used for research when the animals developed a "pox-like" infection, hence the name. Since May, several non-endemic countries have reported human cases of the monkeypox virus, including the United Kingdom, the United States, Portugal, Spain, and Italy.
Affected by the ever-changing international situation, the supply and prices of international bulk concrete foaming agent are still very uncertain.
Foam concrete natural maintenance can be divided into two types: cover-up sprinkler maintenance and plastic film maintenance.
Cover-up sprinkler maintenance:
It is that according to the external temperature, the concrete should be covered with appropriate data such as grass curtain, Reed mat, sack, sawdust, wet soil and wet sand within 12 hours after the end of foam concrete pouring, and often sprinkle water to keep it wet.
Foam concrete sprinkling maintenance cycle: for Portland cement, general cement and slag cement mixed concrete shall not be less than 7 days and nights; concrete mixed with slow setting admixture or impermeable request shall not be less than 14 days and nights; when using bauxite cement, not less than 3 days and nights. The frequency of watering every day has been able to insist that the concrete has a satisfactory wet condition. When the temperature is above 15 °C, the concrete should be sprinkled at least once every 3 hours during the day and twice at night when the concrete is poured. In future maintenance, sprinkling water at least 3 times a day (of course, when the temperature is dry, the frequency of watering can be appropriately increased).
For large area (or volume) concrete, we should choose "water storage maintenance". Projects such as storage tanks can be maintained by sprinkling water after the internal mold is removed and the concrete reaches a certain strength; with regard to the underground structure or foundation, it is possible to paint asphalt emulsion or backfill with soil instead of sprinkler maintenance.
Plastic film maintenance:
It refers to the use of plastic film cover material to separate the concrete from the air, water is no longer transpirated, cement depends on the moisture in the concrete to complete the hydration effect has reached condensation hardening.
This method can directly cover the plastic draft on the appearance of the concrete, or spray the plastic emulsion on the instant noodles of the concrete members, and wait until the emulsion is transpirated, and then combine into a layer of plastic film on the surface of the concrete to block the concrete members from the air, so that the moisture in the concrete will no longer transpirate and complete the hydration effect. The defect of spraying plastic film maintenance is the low strength of concrete. And because the film is thin, can not fully achieve the effect of insulation, freezing, so in the summer when using this method is to add sunscreen equipment (not less than 24 hours), otherwise it will cause filamentous cracks in foamed concrete.
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Cancer cells can "stretch out a big hand" and take away the mitochondria of immune cells. The Harvard Medical School research team cultured mouse and human breast cancer cells and immune cells, such as killer T cells, and used field emission scanning electron microscopy (FESEM) to observe the relationship between cancer cells and immune cells. interactive. Interestingly, they found that cancer cells stick out long nanotubes, typically within 100-1000 nanometers in diameter, each of which connects to multiple immune cells along the way. The researchers used the drug L-778123, which inhibits the formation of nanotubes, for treatment. The higher the concentration of L-778123, the better the treatment effect.
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